1. All applications require optimization of amplitude and time settings. Test your probe/tip with water using the same volume and sample vessel that you will use for actual sample processing. Observe how the liquid moves during sonication at different amplitude (intensity) settings. You should see and hear the cavitation and the entire sample volume should mix and flow well.

2. Choose an amplitude setting that does not create foam or splashing as your starting point. Smaller volumes will require lower amplitude settings and shorter pulses of sonication. Larger volumes can be sonicated at 100% if necessary, to speed up processing times.

3. After choosing an amplitude setting, perform a time study by testing a sample at several time intervals and comparing results. Adjust amplitude and time as needed to obtain the desired result.

4. Contact our aftersales team for Protocols and Papers from other customers.